BIOPERINE

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In Studies (Black pepper - piper nigrum fruit extract) increases absorption of other nutrients from 30 to 250% via process called thermogenesis.

Recent studies have shown that it can greatly increase the bioavailability of other compounds – such as vitamins, minerals and herbal substances.

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BORAGE OIL

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Borage Oil is nature's best source of GLA.

Borage Oil is nature's richest source of the nutritionally important Omega-6 fatty acid GLA. Clinical research shows that Borage Oil, with its unusually high GLA content, maintains healthy moisturized skin joint flexibility and prostate health by reducing inflammation. In Japan, medical claims have been made for its use in maintaining healthy skin function and cholesterol levels.

BORON

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Help protect the health of the prostate gland.

When examining the data from the National Health and Nutrition Examination Survey (NHANES), researchers uncovered a significant relationship between boron and prostate health. After comparing the diets of nearly 8,000 men, they found that the risk of prostate diseases for men consuming an average of 1.8 milligrams of boron was less than one-third the risk for men consuming half that amount.

CAT’S CLAW

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Cat's claw, also known as una de gato (its Spanish name), is a high-climbing, woody vine that grows profusely in the upper Amazon regions of Peru, Columbia, Ecuador, and other South American countries. At the base of the plant's leaves are two curved thorns that resemble the claws of a cat (hence its name); these allow the vine to climb up trees and other vegetation into the forest canopy. The herb's botanical name, Uncaria, is from the Latin uncus, for "hook."

Two species of cat's claw are harvested for medicinal purposes, Uncaria guianensis, used mainly in Europe, and Uncaria tomentosa, commonly imported into the United States. Among the herbal practitioners of South America, the two species are considered interchangeable.

For hundreds of years, people in the Amazon basin have used cat's claw to treat a broad range of ailments, ranging from arthritis, and stomach and liver disorders to skin conditions and even contraception. Traditionally, the herb's primary medicinal form has been a decoction, or crude extract, prepared by boiling the inner bark of the stem and parts of the root.

Scientific interest in cat's claw centers on the plant's immune-boosting and anti-inflammatory properties. There is early and speculative evidence that cat's claw may have antiviral.

In recent years researchers have identified two separate subspecies of U. tomentosa, which have important differences in their chemical properties. One contains mainly pentacylic alkaloids, substances responsible for the most well-researched effect of cat's claw, namely immune stimulation. The other type of U. tomentosa contains tetracylic alkaloids, which affect the brain and central nervous system and actually counteract the immune-stimulating effects of the pentacylic group.

Health Benefits

In the mid-1990s, once it became known that cat's claw had potential value for the treatment of serious conditions such as arthritis, and even HIV infections, it became one of the top-selling herbs in the United States. Unfortunately, this enthusiasm was not backed up by much clinical evidence. Very few well-designed clinical trials with human subjects have been done on cat's claw, but some laboratory and animal studies have been conducted.

Most of the anecdotal evidence (word of mouth only) indicates that it may help to improve inflammatory problems such as osteoarthritis (OA) and prostatitis, immune disorders such as lupus and rheumatoid arthritis (RA), and situations in which a stronger immune system is desired, such as HIV. On the other hand, some herbal researchers also point out that long-term use of cat's claw might overstimulate the immune system and do more harm than good for some of these conditions.

According to a 2001 article in Alternative Medicine Review, cat's claw also warrants further research because of the worldwide concern over viral diseases. Although these areas have not been fully explored, some experts believe that cat's claw may eventually have potential in fighting chronic viral infections such as AIDS, and also in combating immune-related conditions associated with aging.

Specifically, cat's claw may help to:

• Reduce inflammation. In several laboratory experiments, cat's claw has been shown to demonstrate anti-inflammatory effects; few clinical studies of these properties have been conducted, however. One small four-week trial, reported in the 2001 Inflammation Research journal, found that 30 people with OA of the knee had significant relief from pain during daily activities but no easing of nighttime pain or pain during rest; the control group had no pain relief at all. A number of other inflammatory conditions are also being investigated in association with cat's claw, including allergies and asthma, Crohn's disease, rheumatoid arthritis, bursitis, and tendinitis.

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However, Bettuzzi isn't recommending that men start treating themselves with green tea or green tea supplements. He said to consume an amount equivalent to that used in the study, you would have to drink 12 to 15 cups of tea daily, and that while supplements are commercially available, their quality cannot be assured and they may contain caffeine, or more alarmingly, pesticides or other contaminants.

"This is a very interesting observation that deserves to be studied further," said Dr. Jay Brooks, chairman of hematology and oncology at the Ochsner Clinic Foundation Hospital in New Orleans. But, he added, "Personally, I am not recommending that my patients do this."

Bettuzzi also said his findings need to be confirmed in a larger study.

CHRYSIN
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Chrysin (5,7- Dihydroxyflavone) is a potent bioflavonoid found in the plant Passiflora coerula, a member of the passion flower family. Chrysin is the most powerful of several flavonoids that have been tested and found to exhibit anti-estrogenic activity in-vitro by inhibiting the aromatization process. This product has been shown to have a significant effect in modulating the response to stress. It binds to receptors in the brain known as the benzodiazepine specific receptor sites. As a result, Chrysin can aid athletes in dealing with the stress of training.

DIM (DI-INDOLYL METHANE)
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DIM (Di-Indolyl Methane) increases the good estrogen metabolites and decreases the bad estrogen metabolites

Supplementing the diet with DIM and eating cruciferous vegetables increases the specific aerobic metabolism for estrogen, multiplying the chance for estrogen to be broken down into its beneficial, or "good" estrogen metabolites. These "good" estrogen metabolites are known as the 2-hydroxy estrogens. Many of the benefits that are attributed to estrogen, which include its ability to protect the heart and brain with its antioxidant activity, are now known to come from these "good" metabolites.

When DIM increases the "good" estrogen metabolites, there is a simultaneous reduction in the levels of undesirable or "bad" estrogen metabolites. These include the 16-hydroxy estrogens.

Greater production of these "bad" estrogen metabolites is promoted by obesity and exposure to a number of manmade environmental chemicals. These "bad" estrogen metabolites are responsible for many of estrogen's undesirable actions in women and men, including further unwanted weight gain.

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EVENING PRIMEROSE OIL BUY NOW!

Support Prostate health.

Native to North America, the evening primrose is a tiny and short-lived wildflower and not a true primrose. When Europeans found it and took it to Europe, its purported healing properties for skin diseases and flesh wounds quickly earned it the name "King's cure-all." Evening primrose is now grown in 30 or more countries, and the oil pressed from its seed is marketed as a nutritional supplement and as a great source of linoleic acid. Evening primrose oil, however, is a source not only of linoleic acid but also of another kind of fatty acid called gamo-lenic acid (also known as gamma linolenic acid, or GLA). This fatty acid, normally manufactured by the body from linoleic acid, is important in many ways. It is transformed by the body eventually into eicosanoids, hormone-like chemicals that include the prostaglandins. Prostaglandins help control such processes as inflammation, blood clotting, and cholesterol synthesis.

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L ALANINE L GLYSINE AND L GLUTAMIC ACID BUY NOW!

Research has shown that these 3 Amino acids taken in combination are capable of dramatic improvement in BPH. These amino acids were tested in a double-blind study of patients with enlarged prostates. Half of the patients were treated with the combined amino acids the others with a placebo (completely inactive pills given for comparison purposes). 93% of the group taking the amino acids experienced a reduction of prostate enlargement and 95% experienced fewer problems in urination.

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LINUMLIFE - FLAX LIGNANS BUY NOW!

LinumLife is an extract from flaxseed that is highly concentrated in lignans. LinumLife provides between 10 to 30 times more lignans than whole flaxseed or other flax ingredients.

The main lignan in flax is secoisolariciresinol diglucoside, or SDG. When ingested, micro-organisms in the colon convert SDG into enterodiol and enterolactone, the so-called mammalian lignans. These are the body’s own active forms of lignans.

Characteristic for phytoestrogens, lignans can weakly bind to estrogen receptors. A sufficient level of these lignans can compete with natural estrogen for the estrogen receptors, resulting in balanced estrogen levels in the blood. This basic mechanism has different effects in men and women.

Lignans for Men's Health

Lignans have many potential benefits for men, specifically in areas related to prostate health. A great deal of attention is being focused on benign prostatic hyperplasia (BPH) because it is a growing public health problem. The American Urological Association estimates that BPH affects 50 percent of men aged 50 to 60 and up to 90 percent of men over the age of 80. This can be a problem because the urethra, the tube carrying urine from the bladder to outside the body, runs through the prostate (see illustrations). A growing prostate can pinch off the urethra and cause uncomfortable symptoms, like a frequent and overwhelming urge to urinate, and painful urination. The exact cause of BPH is unknown, but male hormones seem to play a role. In the body, testosterone is converted to a more potent form called dihydrotestosterone or DHT. Normal, healthy prostate cells require DHT for growth. However, it is thought that too much of this hormone can cause abnormal growth—leading to BPH . Therefore, compounds that interfere with the conversion of testosterone to DHT could reduce a man's chances of developing these diseases.

Lignans have been shown to block the action of the enzyme that converts testosterone into DHT. 2 Lignans may also reduce the amount of testosterone available for the body to use. In the average male, only a small amount of testosterone roams free in the blood. Most testosterone is bound to a protein called SHBG (sex hormone binding globulin). People who consume large amounts of lignans have been shown to have increased blood levels of SHBG.3 An increase in SHBG leaves less testosterone available to stimulate prostate cell growth.

Lignans and hair loss

Androgenetic alopecia (AGA) is the most common type of hair loss in men and women. AGA can be defined as a testosterone dependent process.

When a hair is shed, the active form of testosterone (DHT) initiates the miniaturization of hair root and follicle. Lignans balance DHT levels and thereby prevent hair follicles from being miniaturized.

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LYCOPENE BUY NOW!

• Lycopene is an open-chain unsaturated carotenoid that imparts red colour to tomatoes, guava, rosehip, watermelon and pink grapefruit.

• Lycopene is a proven antioxidant. Antioxidants neutralize free radicals, which may damage the body's cells.

• Research shows that lycopene in tomatoes can be absorbed more efficiently by the body if processed into juice, sauce, paste and ketchup. The chemical form of lycopene found in tomatoes is converted by the temperature changes involved in processing to make it more easily absorbed by the body.

• In the body, lycopene is deposited in the liver, lungs, prostate gland, colon and skin. Its concentration in body tissues tends to be higher than all other carotenoids.

• Regular high consumption of fruits and vegetables is recommended as part of healthy eating.

• Ongoing preliminary research suggests that lycopene is associated with reduced risk of macular degenerative disease, serum lipid oxidation.

• Studies are underway to investigate other potential benefits of lycopene - including the H.J. Heinz Company sponsored research at the University of Toronto and at the American Health Foundation.

MARINE LIPID CONCENTRATE DHA EPA
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One of the healthiest low-fat proteins is fish. But fish and fish oil aren't only a healthy option for loosing weight-they may help your prostate health because they're high in DHA and EPA.

Ocean fish body fat is rich in the omega-3 fatty acids DHA and EPA. These fatty acids block the conversion of arachidonic acid to these potentially damaging products and, as a result, have multiple health benefits. In fact, increasing dietary DHA and EPA may alleviate the symptoms of arthritis and other types of inflammation; it also decreases the tendency of platelets to trigger blood clots, and, in turn, reduces the risk of stroke. And over the past year, researchers showed that increasing your intake of DHA and EPA can dramatically reduce your risk of cardiac arrest because of abnormalities in heart contraction rhythm.

But some of fish oil's health benefits appear to be unrelated to its ability to block the arachidonic acid metabolism. For example, DHA appears to play a critical role in the development and function of the human brain and retina. As a result, DHA supplements are routinely added to pediatric formulas used to replace human milk.

Fish do not make DHA and EPA but obtain it from algae that form the bottom of the ocean food chain. In algae, these omega-3 fatty acids act to keep the membranes of the plants flexible and fluid at cold temperatures. Thus, fish that live in cold water are better sources of these omega-3 fatty acids than fish from tropical regions.

ORGANIC FLAX OIL
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Flax has been used for thousands of years for food, clothing and linen but only recently have studies uncovered the nutritional benefits of Flax. With high levels of Omega-3 Fatty Acids, lignans and fiber, Flax provides nutritional benefits that are important to overall health. Flax Oil is nature's most potent source of Omega-3 EFAs . Studies show that Omega-3 EFAs support cardiovascular health and joint flexibility.*

When looking at flax products, it is important to recognize the nutritional differences found in various flax products, be it Flax Oil, Flax Lignans or Flax Fiber. Supplementspot works hard to guarantee their flax products are the highest level of quality in the industry.

Omega-6 Fatty Acid or Linoleic Acid has been recently shown to significantly educe the risk of stroke.

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PANAX GINSENG
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This supplement is widely taken to help your body deal with stress. Ginseng also increases stamina and energy and has even shown to increase testosterone levels. When you consider it also has a positive effect on blood flow, it's easy to see why ginseng would have a valuable effect to maintain an erection.

Used in the Orient for hundreds of years and reputed to aid virility and improved sex life. Research showed it to increase testosterone levels whilst reducing prostate size.

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RESVERATROL

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Resveratrol is a compound produced by many plant species and is thought to be helpful in reducing serum lipids and may have favorable cardiovascular implications. It is produced by Vitis vinifera and labrusca grapes and is found in grape products including red and white wines. Resveratrol has been proven effective in extending life up to 30% and is key in the prevention of many types of heart disease.

Resveratrol is studied by nutritionists and biochemists because of its potential as a cardioprotective compound. Resveratrol belongs to the phytoalexin class of phytochemicals and functions as a moderate antioxidant, quenching free radical damage . The compound has also demonstrated anti-inflammatory properties.

In humans, studies are underway to determine health benefits of resveratrol in heart disease. Preliminary research results demonstrate that resveratrol may have anti-infective, antioxidant, and anti-inflammatory properties. According to studies involving mice, resveratrol seems to reduce the occurrence of skin tumors.

SELENIUM BUY NOW!

News from the NCI

National Institutes of Health

Office of Communications
Building 31, Room 10A19 Bethesda, MD 20892
12:01 a.m. EDT , Tuesday, July 24, 2001
NCI Press Office
(301) 496-6641
Southwest Oncology Group
(210) 677-8808

• Men in the study will visit their study site once every six months. Upon enrollment, they will be assigned by chance to one of four groups. One group will take 200 micrograms of selenium daily plus an inactive capsule, or placebo, that looks like vitamin E. Another group will take 400 milligrams of vitamin E daily along with a placebo that looks like selenium. A third group will take both selenium and vitamin E. And a final group will be given two placebos.

• Men who join SELECT will not need to change their diet in any way, but they must stop taking any supplements they buy themselves that contain selenium or vitamin E. If participants wish to take a multivitamin, SWOG will provide without charge, a specially formulated one that does not contain selenium or vitamin E.

• Men may be able to participate in SELECT if they:

  • Are age 55 or older; age 50 or older for black men.

  • Are generally in good health

Health Benefits Of Selenium

Selenium:

Selenium and cardiovascular disease:

• Based on epidemiological data, a lower antioxidant status has been linked to higher incidence of cardiovascular diseases due to increased levels of LDL oxidation. Selenium is one of the antioxidants that may help to inhibit LDL oxidation.

• The National Academy of Sciences (NAS) released a report on April 11th reviewing the emerging science of antioxidants and their potential for disease protection. The Council for Responsible Nutrition Concludes that while there is not enough scientific evidence to permit recommended intakes based on disease prevention, the wide range of safe intakes for antoxidant vitamins is approved. It issued higher Recommended Dietary Allowances(RDAs) for vitamins C and E. The new RDAs for antioxidant nutrients are: vitamin C (75 milligrams (mg) for women and 90 mg for men), vitamin E (15 mg), and selenium (55 micrograms (mcg)).

• The report stated that there is "reason to expect that the antioxidant vitamins (C and E) should decrease the risk of cardiovascular disease." The report concluded that vitamin E does inhibit LDL oxidation (a causative agent for cardiovascular disease) and could also affect the health of arteries in other ways. The report also noted that it is reasonable to expect that vitamin C would reduce oxidative damage to the eye, thus lessening the risk of cataracts and other conditions.

• The NAS report also established tolerable upper intake levels (ULs) for vitamin C (2,000 mg), vitamin E (1,000 mg) and selenium (400 mcg). ULs for adults are set to protect the most sensitive individuals of the general population.

Selenium and healthy blood sugar levels

• Selenium is reported to mimic the action of insulin. In laboratory studies performed in recent years, selenium has been shown to mediate a number of insulin-like actions such as stimulating glucose uptake and regulating metabolic processes including glycolysis, gluconeogenesis, fatty acid synthesis and the pentose phosphate pathway. Although the exact mechanism of the insulin mimicking action of selenium has as yet to be elucidated, it is reported that these actions are mediated through the activation of key proteins involved in the insulin-signal cascade. Selenium is also reported to play a role in reducing the oxidative stress associated with diabetes, thereby retarding the progression of the secondary complications of diabetes such as neuropathy, retinopathy and cataracts.

Selenium and arthritis

• Low selenium status has been associated with the incidence of arthritis. Preliminary studies indicate the beneficial role of selenium as a free radical scavenger that may delay the progression of arthritis.

Selenium and HIV

• Malabsorption leading to deficiency state ahs been observed in cases of progression of HIV /AIDS. 24 children with HIV were observed for a period of five years. Those with low selenium levels had greater risk of mortality.

Selenium and Alzheimer's

• Low plasma selenium status has been associated with senility and cognitive decline in the elderly and with Alzheimer's disease. Selenium supplementation was observed to reduce the severity of epileptic seizures in children. Selenium supplementation is also reported to improve confused and depressed mental states; mental fatigue and anxiety in adults.

Deficiency Diseases

Musculo-skeletal and circulatory disorders

• Selenium deprivation is reported to reduce the activities of the selenium-dependent antioxidant enzymes, leading to a number of functional disorders.

• Vitamin E-deficient animals in the presence of selenium deficiency show dysfunction of skeletal muscles (observed in sheep, cow, horse), cardiac muscles (observed in pig), or smooth muscle (observed in dog, cow), hepatic degradation (observed in rat, pig), increased capillary permeability (observed in chicken), or pancreatic degeneration (observed in chicken).

• Very low selenium status is a factor in the etiologies of a specific type of juvenile cardiomyopathy (Keshan's Disease) and a chondrodystrophy (Kaschin-Beck Disease) that were observed in selenium-deficient regions of China.

A compromised immune system : Increased susceptibility to diseases

• Low plasma selenium levels were observed in patients with bacterial and viral infections.

• A clinical study on 53 patients determined that in bacterial infections (septicaemia, pneumonia, erysipelas and meningitis) the plasma concentrations of selenium, iron and zinc were found to be decreased.

• Selenium deficiency may increase the incidence of viral diseases such as HIV infection, Ebola virus infection and others. Selenium is reported to counteract the development of virulence and inhibit HIV progression to AIDS.

• Infection with the ebola virus is associated with hemmorhagic symptoms. The synthesis of viral selenoproteins is reported to be responsible for these symptoms. One potential viral selenoprotein may contain up to 16 selenium atoms per molecule. The demand for selenium in this synthesis depletes the selenium resources of the human host, leading to severe lipid peroxidation and cell membrane destruction, and contributing to hemorrhagic symptoms.

• In experimental studies, selenium deficiency was found to be associated with a nearly threefold higher likelihood of genital mucosal shedding of HIV-1--infected cells, suggesting that deficiency may increase the infectiousness of women with HIV-1.

• This finding corroborates earlier observations of Ebola outbreaks in selenium-deficient areas of Africa.

• A recent study on mice revealed that Selenium deficiency increases the pathology of an influenza virus infection. Infected Selenium-deficient mice developed much more severe interstitial pneumonitis than did Selenium-adequate mice and showed a weakened immune system response. The authors concluded that these results demonstrate that adequate nutrition is required for protection against viral infection and suggest that nutritional deprivation may be one of many factors that increase the susceptibility of individuals to influenza infection.

Impaired thyroid functions

• Selenium deficiency may also affect thyroid functions as the active thyroid hormone is synthesized in the presence of the enzyme thioredoxin reductase, of which selenium is an essential constituent.

• Selenium deficiency may aggravate the effects of iodine deficiency on thyroid functions.

• Adequate selenium status is reported to offer protection against some of the neurological effects of iodine deficiency.

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SOY ISOFLAVONE EXTRACT 40% BUY NOW!

Soy Isoflavones effectively Reduce Risk of Heart Disease.

SOY ISOFLAVONES have been in the news recently for their known help in lowering cholesterol and reducing the risk of heart disease. This supplement is also important for prostate health. The main constituents in soy that are helpful are genistein and daidzein. These are NOT "Phytoestrogens" as many so-called experts will allege as there is no estrogen, or testosterone, progesterone, DHEA, melatonin in any plant.

Studies on prostate health and isoflavones have been published in journals such as Prostate. The proof is overwhelming.

Isoflavones have what you need, not only for prostate health, but to also to prevent high cholesterol and heart disease.

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STINGING NETTLE ROOT (URTICA DIOICA) BUY NOW!

Stinging Nettle root is an herb with stinging hairs found in the United States mostly in forests, mountains, weedy, undisturbed areas and roadsides. Extracts of the stinging nettle roots have been used in Germany for the therapy of prostate disorders and rheumatoid arthritis.

What's in Stinging Nettle?

Extracts from stinging nettle contain a number of substances including caffeic acid, malic acid, polysaccharides and probably many other compounds including lectins, lignans, and phytosterols.

Stinging Nettle benefits

Stinging nettle has been shown to inhibit the body from making certain inflammatory chemicals known as prostaglandins. Stinging nettle’s root may affect hormones levels and proteins in the blood that carry sex hormones (such as testosterone or estrogen). One study described later found the combination of stinging nettle and saw palmetto was as good as finasteride (Proscar) in reducing symptoms of prostate enlargement. Stinging nettle appears to also have antioxidant properties.

As men age, their ratio of estrogen to testosterone increases, making it important to inhibit the effects of estrogens, sex hormone binding globulin (SHBG), and dihydrotestosterone (DHT).

Stinging Nettle root helps to inhibit the proliferation of prostate cells in response to estrogen and SHBG.

The prostate gland also benefits from Stinging Nettle root. In Germany, Stinging Nettle root has been used as a treatment for benign prostatic hyperplasia (enlargement of the prostate gland) for decades. A metabolite of testosterone called dihydrotestosterone (DHT) stimulates prostate growth, leading to enlargement. Stinging Nettle root inhibits the binding of DHT to attachment sites on the prostate membrane.

Stinging Nettle root extracts also inhibit enzymes such as 5-alpha Reductase that cause testosterone to convert to DHT. It is the DHT metabolite of testosterone that is known to cause benign prostate enlargement, excess facial hair, and hair loss at the top of the head.

ZINC PICOLINATE

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Zinc helps tissues grow and repair themselves. In addition to helping heal wounds faster, zinc is probably the most important mineral for keeping the immune system strong. Too little zinc can lead to a drop in infection-fighting white blood cells, which can increase your risk of getting sick. On the other hand, too much zinc may interfere with the workings of another trace mineral you need: copper. As with most minerals, high intake may prove toxic, and too much zinc can damage the immune system. Take no more than 90 milligrams of zinc per day.

Zinc Picolinate is the form use in this formula. It is a highly absorbable and bio-available form of Zinc.